|
|
{PRIVATE}
|
No. of Infants
|
Score
|
|
Low forceps or spontaneous
|
843
|
8.4
|
|
Cesarean section
|
141
|
6.8
|
|
Midforceps delivery
|
17
|
6.9
|
|
Breech delivery
|
16
|
6.7
|
|
Version and breech extraction
|
4
|
6.3
|
The infants in the best condition one minute after birth are those born vaginally with the occiput
the presenting part. The incidence
of the use of low forceps in this clinic is 34 per cent and after a two year daily observation of routine
deliveries it did not seem to
be of value to separate the spontaneous deliveries from those in which low forceps were used. Delivery
by any other means
produced no difference in the infants. The score for all these was slightly less favorable than those
born spontaneously or with low
forceps.
Cesarean Sections. -- The cesarean section rate at Sloane Hospital is 10.5 per cent during
this period. The anesthesia
methods for the 141 rated infants born by cesarean section are listed:
|
{PRIVATE}
|
Infants
|
Average Score
|
|
Spinal anesthesia
|
83
|
8.0
|
|
General anesthesia
|
54
|
5.0
|
|
Epidural or caudal
|
4
|
6.3
|
The method used for spinal anesthesia was a single dose of nupercaine 0.25 per cent made hyperbaric
with dextrose, in doses
ranging from 6 to 7.5 mg, or pontocaine 0.3 per cent, hyperbaric, from 7 to 9 mg. A 22
gauge needle was used. No
supplementary anesthesia was given to these patients until after the birth of the infant. General
anesthesia in all cases was
accomplished with cyclopropane and oxygen. In 20 cases to be discussed later a relaxant
was used with cyclopropane.
Fractional epidural or caudal anesthesia (0.75 per cent xylocaine) was continued in 4 cases for cesarean
section after a trial of
labor.
The indications for general anesthesia in cesarean section are thought to be a history of syphilis, septicemia. severe hemorrhage, or a history of traumatic experience with spinal anesthesia. Although this method does not take into account maternal risk or antepartum fetal problems, it is apparent that the mothers of the potentially poor risk infants received spinal anesthesia. In spite of this and the frequent maternal hypotension, the condition of the infants after spinal anesthesia was definitely better than after general anesthesia.
The average time for delivery of the infant after induction of general ansthesia was fourteen minutes
and twenty-four minutes after
the administration of spinal anesthesia.
There is questionable support of the theory [10] that infants who have been subjected to a trial of
labor are in better condition than
those in whom cesarean section was chosen electively, as indicated below.
|
{PRIVATE}
|
Infants
|
Average Score
|
|
Patients in labor
|
57
|
7.1
|
|
Patients not in labor
|
84
|
6.7
|
These small groups have been analyzed statistically [11] and are not statistically significant.
In obstetric circles there has been the subtle impression that the lower the cesarean section rate in
a clinic, the better was the
practice of obstetrics. There is a slight trend away from this idea, and that at times even cesarean
section is a conservative form
of therapy. [12]
We have felt that with individual attention to selection of anesthetic agents and their administration
by competent
anesthesiologists, that infant survival after elective cesarean section might be made as successful
as after an uncomplicated
vaginal delivery. That we have not yet reached this point is illustrated in the next table. The
group of cesarean section patients
who had no antepartum problems and in whom labor was not present (secondary and tertiary sections) was
compared with a
similar group of vaginal deliveries in whom no problems of any kind were apparent. All received spinal
anesthesia.
The condition
of the infants delivered vaginally was better than those delivered by cesarean section.
|
{PRIVATE}
|
Infants
|
Average Score
|
|
Normal, elective sections
|
38
|
7.7
|
|
Normal, low forceps or spont.
|
38
|
9.0
|
The most obvious difference between the two groups is the presence of labor in those delivered vaginally
and the absence of
labor in the section group. We do not know whether this implies some beneficial effect of labor on respiration,
circulation and
general well-being of the infant.
The experimental reports on the lack of placental transfer of d-tubocurarine, flaxedil, decamethonium
[13, 14, 15, 16] are
intriguing. Several clinical reports seem to bear out this somewhat surprising finding. Other papers
are in disagreement. [17]
In an effort to test this possibility clinically, 20 patients received a relaxant intravenously
as a means of keeping the patient from
moving, accompanied by as light a plane of cyclopropane as would produce unconsciousness.
Seventeen received d-tubocurarine, and 1 patient each received flaxedil, succinylcholine
and decamethonium bromide. Thirteen infants were
rated.
|
{PRIVATE}
|
Infants
|
Average Score
|
|
Sections: Cyclopropane without relaxant
|
41
|
5.0
|
|
Sections: Cyclopropane with relaxant
|
13
|
5.0
|
In addition to the fact that there was no difference in the infant's condition with or without the use
as a relaxant, 70 per cent of the
infants with relaxant needed oxygen administration in some form, while the
number needing oxygen after cyclopropane
anesthesia alone was likewise 70 per cent. The infants are not in better condition with relaxants
and nothing is to be gained by
the use of curare or similar drugs for cesarean section anesthesia. The occasional maternal respiratory
depression necessitating
assisted respiration is a distinct disadvantage to the technique.
Breech Deliveries. -- There were 16 cases of breech deliveries excluding twins and version
and breech extraction. All but one
who precipitated without anesthesia were anesthetized with general anesthesia in a plane as light as
compatible with the
obstetric maneuvers.
Nitrous oxide, ethylene or cyclopropane were used for this purpose
. The average score was 6.7,
essentially the same as for cesarean section infants. Regional methods were not used in this small group.
Twins. -- Nine pairs of twins were delivered by a variety of methods. The average score
of the 18 babies was remarkably good,
8.6, and probably
reflects the use of
minimal medication during the final stage of labor
. The use of regional anesthesia,
however, again produced better results than general anesthesia in this small series.
|
{PRIVATE}
|
Infants
|
Average Score
|
|
Twins, general anesthesia
|
14
|
8.2
|
|
Twins, regional anesthesia
|
4
|
9.8
|
The condition of the first twin was somewhat better than the second.
|
{PRIVATE}
|
Infants
|
Average Score
|
|
Twin A
|
9
|
8.9
|
|
Twin B
|
9
|
8.2
|
Midforceps Delivery
. -- The condition of the infants following midforceps delivery was the same as by section or by
breech
delivery. There was no difference relating to the anesthetic method.
|
{PRIVATE}
|
Infants
|
Average Score
|
|
Midforceps, general anesthesia
|
11
|
6.8
|
|
Midforceps, regional anesthesia
|
6
|
7.0
|
Low Forceps and Spontaneous Deliveries
. -- This large group showed some improvement in the infant's condition following the
use of regional anesthesia
.
|
{PRIVATE}
|
Infants
|
Average Score
|
|
General anesthesia
|
692
|
8.2
|
|
Spinal anesthesia
|
25
|
8.9
|
|
Epidural, caudal anesthesia
|
102
|
9.1
|
|
Pudendal or no anesthesia
|
24
|
9.2
|
Prematurity
There were 70 infants in this series whose birth weights were between 500 and 2500 grams. The nonviable premature infants, under 500 grams, were excluded and considered to be abortions.
The youngest child who has survived in the Premature Nursery of the Babies Hospital weighed 580 grams. Regional anesthesia again was associated with a better score for the child.
|
{PRIVATE}
|
Infants
|
Average Score
|
|
Premature, general anes.
|
44
|
8.0
|
|
Premature, regional anes.
|
24
|
9.2
|
|
Premature, no anes. ppt.
|
2
|
2.0
|
Resuscitation
Oxygen, suction, some method of positive pressure, endotracheal tubes and an infant laryngoscope are present in every delivery room. Oxygen was used freely if the infant's condition was not good. The three types of administration used are:
(1) Face oxygen, in which method oxygen is added to inspired air, but without increase in pressure at
the face.
(2) Positive pressure mask, in which a small mask is held snugly on the infant's face, and some degree of positive pressure is applied to the pharynx.
(3) Endotracheal oxygen, in which direct laryngoscopy is performed, additional suction used if necessary, and intubation (to treat by inserting a tube) accomplished. Positive pressure usually with added oxygen is implied in this method.
The details of these methods and indications for their use as well as discussion of other
resuscitative measures will be the
subject of other communications
.
Three hundred thirty six or 19.4 per cent of the 1733 living infants received oxygen by some method.
Of this group
The survival rate following the use of
endotracheal oxygen ( a thin tube put down the windpipe or trachea)
in this clinic over a 3
year period is between 60 and 70 per cent of the cases in which it has been employed.
The
incidence of the use of oxygen
for the infant following the various routes of deliveries is as follows:
|
{PRIVATE}Cesarean section
|
54 per cent
|
|
Midforceps
|
8 per cent
|
|
Breech delivery
|
37 per cent
|
|
Low forceps and spont.
|
15 per cent
|
In 217 of 336 infants who received oxygen, ratings were obtained and the method of administration was
recorded.
|
{PRIVATE}
|
Cases
|
Average Score
|
|
Face oxygen
|
117
|
6.7
|
|
Positive pressure mask
|
90
|
3.9
|
|
Endotracheal oxygen
|
10
|
2.1
|
In 14 of the group of 117 cases receiving face oxygen, a score of 9 or 10 was given, and these infants
undoubtedly did not need
the oxygen so administered.
Neonatal Deaths
There were 25 neonatal deaths in the entire group of 2096 deliveries , or a rate of 1.2 per cent. If the 38 stillbirths over 500 grams are included, the total fetal loss was 64 infants, or a rate of 3.0 per cent of total infants born. The distribution by type of delivery is as follows:
|
{PRIVATE}Type
|
Cases
|
Neonatal
Deaths |
Per Cent
of Type |
|
Cesarean section
|
220
|
2
|
0.9 per cent
|
|
Breech deliveries
|
54
|
5
|
9.3 per cent
|
|
Low, midforceps and spont.
|
1822
|
18
|
1.0 per cent
|
Fourteen of the infants who died were under 2500 Gm. birth weight, representing a mortality of
7.8 per cent
of the total number of
premature infants born alive. Of the 11 mature infants who died, all had obstetric or medical
reasons for their deaths. In this
series anesthesia complications apparently did not contribute to the death of any case. Twelve of
the infants who later died were
rated at birth and averaged 2.3 points.
In order to check the approximate accuracy of the various scores, the fate of the infants in poor, fair
and good condition was
examined. After this initial experience, it seems to us that groups 8, 9, and 10 indicate infants in
good condition, 0, 1, and 2, poor
condition, and the remaining scores, fair condition.
|
{PRIVATE}Score
|
Infants
|
Deaths in this Group
|
|
0, 1, or 2
|
65
|
9 or 14 per cent
|
|
3, 4, 5, 6, or 7
|
182
|
2 or 1.1 per cent
|
|
8, 9, or 10
|
772
|
1 or 0.13 per cent
|
Thus, the prognosis of an infant is excellent if he receives one of the upper three scores,
and poor if one of the lowest 3 scores
.
From this we may also conclude that color as a sign is relatively
unimportant when observed one minute after birth
.
Summary
A practical method of evaluation of the condition of the newborn infant one minute after birth has been described. A rating of ten points described the best possible condition with two points each given for respiratory effort, reflex irritability, muscle tone, heart rate and color. Various applications of this method are presented.
The author wishes to acknowledge gratefully the assistance and encouragement of
H. C. Taylor, Jr., M. D. The data were
collected with the technical assistance of Rita Ruane, R.N.
Bibliography
1. Little, D. M., Jr., and Tovell, R. M. Collective Review: A Physiological Basis for Resuscitation of the Newborn, Internat. Abstr. Surg. 86:417-428 (May) 1948.
2. Smith, C. A.: Effects of Birth Processes and Obstetric Procedure upon the Newborn lnfant. Advances In Pediatrics. Interscience Publishers. New York. 1938, vol. 3, chap. 1, pp. 1-54.
3. Kolb, L., and Himmelsbach, C. K.: Clinical Studies of Drug Addiction III, Washington Public Health Reports. U. S. Treas. Dept., 1938, Supplement 128, pp 23-31.
4. Hapke, F. B., and Barnes, A. C.: The Obstetric Use and Effect on Fetal Respiration of Nisentil, Am. J. Obst. & Gynec. 58:799-801 (Oct.) 1949.
5. Eckenhoff, J. E.; Hoffman, G. L.; and Dripps, R. D.: N-allyl Normorphine, an Antagonist to the Opiates, Anesthesiology 13:242-251, (May) 1952.
6. Flagg, P.: The Art of Rescuscitation , New York, Reinhold Publishing Co., 1944, p. 124.
7. Eastman, N. J.: Foetal Blood Studies. I. The Oxygen Relationships of the Umbilical Cord at Birth, Bull. Johns Hopkins Hosp. 47:221-230, 1930 .
8. Apgar , V.: Oxygen as Supportive Therapy in Fetal Anoxia, Bull. N. Y. Acad. Med. 26: 2nd series, 474:478 (July) 1950.
9. Fleming: Personal communications.
10. Bloxsom, A.: The Difficulty in Beginning Respiration Seen in Infants Delivered by Cesarean Section, J. Pediat. 20:215-222 (Feb.) 1942.
11. Frumin, J.: Personal communication.
12. Harris, J. M. et al: The Case of Reevaluation of Indications for Cesarean Section, West. J. Surg. 59:327-356, 1951.
13. Harroun, P., and Fisher, C. W.: The Physiological Effects of Curare, Surg., Gynec. & Obst. 89:73-75, 1949.
14. Young, I. M.: Abdominal Relaxation with Decamethonium Iodide During Cesarean Section, Lancet 1:1052-1053, 1949.
15. McMann, W.: Curare with General Anesthesia for Vaginal Deliveries, Am. J. Obst. & Gynec. 60:1366-1368 (Dec.) 1950.
16. Scurr, C.: A Comparative Review of the Relaxants, Br. J. Anaesth. 23:103-116 (Apr.) 1951.
17. Davenport, H. T.: D-Tubocurarine Chloride for Cesarean Sections: Report of 210 Cases, Br. J. Anaesth. 23:66-80 (Apr.) 1951.
Created 12/8/94 / Last modified 2/5/2000
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